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I had previously taken Quinine when traveling to areas with malaria. Every time the medication worked flawlessly, well at least I have had no cases of malaria. And other people, whom I know travelling to Africa and countries with possible infection risk, also vote for Quinine as an effective medication. It was my family physician who advised me to take the drug, and I am grateful to him for the piece of advice. I have heard of horrible side effects people have with other meds for malaria prevention and treatment. With Quinine everything goes absolutely smoothly and trouble-free, at least in my case it was like this. In other words, I consider Quinine to be a very effective medication for its purpose and I would recommend other travellers to use it.
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Ranque S, Parola P, Adehossi E, Brouqui P, Delmont J: Mefloquine versus 3-day oral quinine-clindamycin in uncomplicated imported falciparum malaria.

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The resistance of Plasmodium falciparum to antimalarial drugs is one of the most worrisome problems in tropical medicine, but few clinical studies or observations have described confirmed cases of therapeutic failure.

Quinine was first synthesized in a laboratory in 1944; however, synthesis of the drug on a commercial scale is not economically feasible.

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According to legend, the man unwittingly ingested quinine while suffering a malarial fever in a jungle high in the Andes.

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If you have had a serious side effect while taking a drug, you or your health care provider can report that side effect to the federal Food and Drug Administration (FDA).

Hydroxychloroquine (Plaquenil) is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine (Aralen) has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used.

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In 2006, WHO changed its guidelines to recommend artesunate for severe malaria in adults.

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We now report on the results of a prospective study conducted to measure the efficacy and tolerability of mefloquine compared to those of quinine plus sulphalene-pyrimethamine (SP; Metakelfin) given for 3 days in adults with uncomplicated falciparum malaria imported from Africa.

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