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These papers, the first of which is a perspective on the second much larger paper, should also be read in conjunction with a recent paper showing the natural product compound equivalents ( invalid metabolic panacea s (IMPS)) to the pan- assay interference compound s (PAINS) that cause major problems in HTS programs.
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The use of chemotherapy is the cornerstone to controlling parasitic infections within human populations; however evidence of sustained control in endemic regions is still limited.
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This review focus on 'the 10 things you should know about protein kinases and their inhibitors', including a short introduction on the history of protein kinases and their inhibitors and ending with a perspective on kinase drug discovery.
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Dedicated to Professors John Blunt and Murray Munro, of the University of Canterbury, for their pioneering work on bioactive marine natural products.
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This review is an updated and expanded version of two prior reviews that were published in this journal in 1997 and 2003.
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OTCAlbendazole: Side Effects See also Benzimidazoles Albendazole, a benzimidazole derivative closely related to mebendazole (qv), is used in the treatment of helminth infections, such as gastrointestinal roundworms, hydatid disease, neurocysticercosis, larva migrans cutanea, and strongyloidiasis.
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