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Out of these, one person taking it with phenytoin and phenobarbital died, twelve became drowsy and four were comatose.
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Primidone, carbamazepine, phenobarbital and phenytoin are among the most potent hepatic enzyme inducing drugs in existence.
In women, none of the metabolic clearances for propranolol showed any significant association with either estradiol or testosterone.
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The following adverse reactions have been observed, but there is not enough systematic collection of data to support an estimate of their frequency.
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There is no published information on the utility of Holter monitoring in infants after initiating propranolol to identify occult bradycardia or arrhythmias, and this group has not reached consensus on a recommendation for Holter monitoring after reaching a steady dose.
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Propranolol is also a substrate of CYP2C19 and a substrate for the intestinal efflux transporter, p-glycoprotein (p-gp).
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Adverse effects, including depression and male impotence, should be monitored in patients on propranolol.
The size of the cohort and details of the study allowed us to quantify the incidence of rebound growth, the nature of rebound, and need for further treatment.
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The VAS tool has been well described as a method for evaluating IH response to treatment in a variety of studies.
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