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To adjust for differences in the change in systolic blood pressure from baseline, the log-transformed urinary albumin-to-creatinine ratio was also analyzed with the use of an ANCOVA model in which treatment and region were variables, with the baseline urinary albumin-to-creatinine ratio and the change from baseline in systolic blood pressure as covariates.
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The present study, by contrast, is the first to compare antihypertensive efficacy as measured by ABPM in more than two ARBs in head-to-head fashion.
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